On 10 March 2023, ECHA’s Public Activities Coordination Tool (PACT) was updated with the following finalised Assessments of regulatory needs (ARN):

1. Tripiperazine dicitrate

2. Piperazinium dihydrogen phosphate

3. Piperazine, compound with phosphoric acid

4. Piperazine dihydrochloride

5. Piperazine adipate

6. Piperazine

7. N,N,4-trimethylpiperazine-1-ethylamine

8. N,N'-bis(3-aminopropyl)piperazine

9. Ethanol, 2-amino-, reaction products with ammonia, 1-piperazineethanamine fraction

10. Diphosphoric acid, compd. with piperazine

11. 2-piperazin-1-ylethylamine

12. 2-methylpiperazine

13. 1-methylpiperazine

14. 1-ethylpiperazine

15. 1,4-dimethylpiperazine

In addition, the PACT was updated with the following finalised Hazard assessment:

1. Quaternary ammonium compounds, tri-C8-10-alkylmethyl, chlorides

This update brought the number of PACT ARN and Hazard assessment substances to 2988.